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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model

Fig. 1

Temporal expression of GPR40, p-PAK4, PAK4, KDM6B, CD16, and CD206 in the brain after GMH. a The representative bands. b–d GPR40, p-PAK4, and KDM6B expression levels decreased significantly from 12 h to 24 h, reaching the lowest point at 24 h after GMH. e CD16 was increased and peaked rapidly at 3 h after GMH, but gradually tended to decrease afterwards. f The expressions of CD206 were upregulated as early as 3 h and gradually increased till 7 days after GMH. **p < 0.01 vs sham. Data are represented as mean ± SD, n = 6 for each group

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