Fig. 8

GW9508 treatment improved memory function but GW1100 reverse the protective function at 21–28 days after GMH. GW9508 administration significantly improved memory function as shown by less a swimming distance, b escape latency, and c percentage of time in the probe quadrant in Morris water maze test, but the swim speed (d) showed no significant difference between the four groups. However, GW1100 reverse the protective function. e Representative thermal imaging of the probe trial. The white circles indicate the positions of the probe platform. *p < 0.05 and **p < 0.01vs Sham, ^@p < 0.05 and ^@@p < 0.01 vs GMH + vehicle, ^#p < 0.05 vs. GMH + GW9508. n = 15