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Fig. 9 | Journal of Neuroinflammation

Fig. 9

From: Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model

Fig. 9

GW9508 attenuated ventriculomegaly and brain atrophy on day 28 after GMH, but reversed by GW1100. GW9508 administration reduced ventricular volume (a and b) and increased relative cortical thickness (c) significantly, but can be reversed by GW1100. ***p < 0.001 vs Sham, @@p < 0.01 and @@@p < 0.001 vs GMH + vehicle, &p < 0.05 and &&&p < 0.001vs GMH + GW9508, one-way ANOVA, Tukey’s test, n = 6

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