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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Expression of SARS-CoV-2-related receptors in cells of the neurovascular unit: implications for HIV-1 infection

Fig. 4

Impact of the SARS-CoV-2 S1 protein subunit on claudin-5 and ZO-1 expression in EC. Human primary endothelial cells were exposed to 15 nM of the SARS-CoV-2 S1 protein subunit for 3, 12, 48, or 72 h and the expression levels of claudin-5 (A) and ZO-1 (B) were measured by immunoblotting. GAPDH was used as a loading control. Graphs indicate the mean ± SD. *p < 0.0449, **p = 0.003; n = 3 per group, three independent experiments

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