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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Interleukin-10 deficiency exacerbates inflammation-induced tau pathology

Fig. 5

Il10 deficiency significantly increased inflammatory cytokine response. Multiplex electrochemiluminescent immunoassay of brain tissue homogenates from Non-Tg or Il10−/− mice described above. A–E Quantification of IL-10 (A), IL-12 (B), IL-1β (C), TNFα (D), and IL-6 (E) cytokines in Veh and LPS-treated mouse brains. Data shown are mean ± SEM of calculated concentration mean (pg/mL/mg); * p < 0.05, ** p < 0.01; *** p < 0.001; two-way ANOVA with Sidak’s multiple comparison test; n = 3–6 mice/group. Hash lines indicate the level of detection (LOD) provided in reagent documentation

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