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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Microglial responses to CSF1 overexpression do not promote the expansion of other glial lineages

Fig. 4

CSF1 OE does not impact the expression of genes expressed in the oligodendrocyte lineage. Quantification of the percent of cells that are OPCs (OLIG2+; PDGFRA+) (A) or mature or maturing oligodendrocytes (OLIG2+; PDGFRA−) (B) in the cerebellar white matter of control (CON, white shaded bars) or CSF1 OE (OE, grey shaded bars) at p14 and 1 year. RT-qPCR for Pdgfra (C), Olig2 (D), and Mog (E) on mRNA isolated from half brain hemispheres of control (CON, white shaded bars) or CSF1 OE (OE, grey shaded bars) mice at p14 and 1 year. ns = non-significant (p > 0.05), unpaired, two-tailed t test

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