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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Increasing toll-like receptor 2 on astrocytes induced by Schwann cell-derived exosomes promotes recovery by inhibiting CSPGs deposition after spinal cord injury

Fig. 2

SCDEs mediates the expression of TLR2 and the release of CSPGs. a Representative images of immunofluorescent analysis of TLR2 (red), astrocyte marker GFAP (green), and DAPI (blue) staining of nuclei in spinal cord lesion site of T10 in sham group, PBS group and SCDEs group at 2 weeks after SCI. Scale bars = 50 μm. b A schematic diagram showing where the images in Fig. 2 were taken from. c Quantitative analysis of the TLR2-positive astrocytes (**P < 0.01, n = 5). d Representative images of immunofluorescent analysis of CSPGs marker CS56 (red), GFAP (green), and DAPI (blue) in different groups at 2 weeks after SCI. Scale bars = 500 μm. Right images are high-resolution versions of the boxed regions in the left images, scale bars = 50 µm. e, f Quantitative analysis of the intensity value of CS56 and CSPGs area (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, n ≥ 6)

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