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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Increasing toll-like receptor 2 on astrocytes induced by Schwann cell-derived exosomes promotes recovery by inhibiting CSPGs deposition after spinal cord injury

Fig. 5

Astrocyte specific TLR2 deficiency decreased the neuroprotective effect of SCDEs after SCI. a Representative images of immunofluorescent analysis of nerve marker PGP9.5 (red), GFAP (green), and DAPI (blue) in each group at 2 weeks after SCI. Right 4 column images are high-resolution versions of the boxed regions in the third column images. Scale bars: left 3 column images = 200 μm. Right 4 column images = 50 μm. b–d Quantitative analysis of nerve gap and the intensity value of PGP9.5 and GFAP (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, n = 6)

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