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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Increasing toll-like receptor 2 on astrocytes induced by Schwann cell-derived exosomes promotes recovery by inhibiting CSPGs deposition after spinal cord injury

Fig. 7

SC-514 abolished the effect of SCDEs on astrocytes distribution, TLR2 expression and release of CSPGs. a Representative images of immunofluorescent analysis of TLR2 (red), GFAP (green) and DAPI (blue) in each group at 2 weeks after SCI. Scale bars = 50 μm. b Representative images of immunofluorescent analysis of CS56 (red), GFAP (green), and DAPI (blue) in each group at 2 weeks after SCI. Scale bars = 200 μm. Right images are high-resolution versions of the boxed regions in the left images, scale bars = 50 µm. c–e Quantitative analysis of TLR2-positive astrocytes, CSPGs area and the intensity value of GFAP (*P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001, n ≥ 5)

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Journal of Neuroinflammation

ISSN: 1742-2094