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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: High-fat diet-induced diabetes leads to vascular alterations, pericyte reduction, and perivascular depletion of microglia in a 6-OHDA toxin model of Parkinson disease

Fig. 4

Effect of HFD on motor impairment. A Amphetamine-induced rotation test, B corridor test, and C cylinder test of sham, moderate, and severe lesion groups on CTRL diet and HFD. Data are expressed in number of ipsilateral turns/min, percentage of contralateral retrievals, and percentage of contralateral touches, respectively. Sham (CTRL diet: n = 5, HFD: n = 4), moderate lesion (CTRL diet: n = 3, HFD: n = 3), severe lesion (CTRL diet: n = 6, HFD: n = 4). Two-way ANOVA: *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; n.s. not significant

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Journal of Neuroinflammation

ISSN: 1742-2094