Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity

Table 1 Demographic information on MSA and control cases

Brain ID	Age	Gender	PMI (hours)	Disease duration (years)
MSA
MSA1	61	Male	21	4
MSA2	82	Male	8	7
MSA3	74	Male	16	10
MSA4	67	Male	11	8
Mean	71 ± 7.8		14 ± 4.9	7.3 ± 2.2
Control
Con1	69	Male	13.5	N/A
Con2	85	Male	9	N/A
Con3	65	Male	14.5	N/A
Con4	88	Male	9	N/A
Mean	76.8 ± 9.9		11.5 ± 2.5

PMI postmortem interval. There was no statistically significant difference in age and PMI between MSA and controls. Statistical test: Student’s t-test

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