Fig. 5
From: TAK1 mediates neuronal pyroptosis in early brain injury after subarachnoid hemorrhage
Blockade of TAK1 prevents neuronal pyroptosis through activating NLRP3 inflammasome. a Representative immunoblot images and b quantification of NLRP3, ASC, cleaved caspase-1, IL-β, and IL-18 in the ipsilateral cortex 24 h after SAH. c Western blotting and d quantitative analysis of NLRP3, ASC, cleaved caspase-1, IL-β, and IL-18 in Ctrl-, OxyHb-, and OxyHb+OZ-treated neurons. Data are expressed as mean ± SD, n = 5 per group. ***P < 0.001 vs Sham group; ##P < 0.01, ###P < 0.001 vs SAH+Vehicle group. †††P < 0.001 vs Control group;§§§P < 0.001 vs OxyHb group