Fig. 6

p38 MAPK and STAT3 pathways mediate TNF-α-induced upregulation of Na⁺ currents in RGCs. a, b Sample traces recorded in an RGC at −20 mV show that pre-incubation of the p38 MAPK inhibitor SB203580 blocked the TNF-α-induced upregulation of peak Na⁺ currents (a), and summary data are shown in b. n = 10. c, d Sample traces recorded another RGC at −20 mV show that pre-incubation of the STAT3 inhibitor stattic blocked the TNF-α-induced upregulation of peak Na⁺ currents (c), and summary data are shown in d. n = 10