Fig. 9

NF-κB signaling pathway mediates TNF-α-induced upregulation of Nav1.6 expression. a Representative immunoblots show the changes in tNav1.6 expression in control (Ctr), TNF-α7D, and SB203580+TNF-α7D retinal extracts (upper panel), and summary data are shown in the lower panel. b Representative immunoblots (upper panel) and summary data (lower panel) of tNav1.6 protein levels in Ctr, TNF-α7D, and stattic+TNF-α7D groups. c Representative immunoblots (upper panel) and summary data (lower panel) of tNav1.6 protein levels in Ctr, TNF-α7D, and BAY 11-7082+TNF-α7D groups. All data are normalized to their corresponding β-actin and then to Ctr. n = 4 for each group. *P < 0.05, **P < 0.01, and ***P < 0.001 vs. Ctr; ^##P < 0.01 vs. TNF-α7D