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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Interleukin-1 blockade attenuates white matter inflammation and oligodendrocyte loss after progressive systemic lipopolysaccharide exposure in near-term fetal sheep

Fig. 6

Representative photomicrographs showing positive staining of GFAP, Iba-1, IL-1β, caspase 3, Olig-2, CC1, MBP and CNPase in the periventricular white matter tracts. Scale bar = 100 μm. Arrows in the Iba-1 photomicrographs indicate microglia displaying a resting ramified phenotype, characterised by a small cell body with > 1 branching process. Arrowheads indicate microglia displaying an amoeboid morphology, characterised by a large cell body with ≤ 1 branching process. Arrows in the caspase-3 photomicrographs indicate positive cells displaying both staining and apoptotic bodies

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