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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Innate immune responses after stimulation with Toll-like receptor agonists in ex vivo microglial cultures and an in vivo model using mice with reduced microglia

Fig. 2

Additional characterization of immune effector secretion by adult microglia when exposed to TLR agonists ex vivo. Adult microglia were exposed to LPS, IMQ, CpG-ODN 1585 (CpG), or medium alone (Med) for 10 h before harvesting. Secreted immune effectors were measured in the harvested medium by Bio-Plex suspension array system. Each dot indicates an individual well of microglia that was isolated from 3 adult mice and cultured separately. Statistical analysis was performed using a one-way ANOVA with an uncorrected Fisher’s least significant difference test to compare P3 to adult microglia exposed to TLR agonists. ****P ≤ 0.0001; ***P ≤ 0.001; **P ≤ 0.01; *P ≤ 0.05

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Journal of Neuroinflammation

ISSN: 1742-2094