Skip to main content

Table 10 Study 2: Differential impact of AIE and galantamine on trophic and proinflammatory factors

From: Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure

Immunoblot marker CON-Veh CON-Gal AIE-Veh AIE-Gal
Pro-BDNF 100% ± 12 97% ± 12 111% ± 14 123% ± 13
Mature BDNF 100% ± 12 116% ± 12 94% ± 14 87% ± 13
Pan-Trk 100% ± 16 75% ± 15 87% ± 20 136% ± 9b
IRβ 100% ± 11 98% ± 11 90% ± 13 103% ± 12
IGF2 Precursor 100% ± 10 127% ± 30 93% ± 15 101% ± 15
Mature IGF2 100% ± 20 86% ± 20 104% ± 23 79% ± 21
Gp91phox 100% ± 17 77% ± 16 131% ± 19a 120% ± 17a
  1. Immunoblot quantification using Li-Cor Odyssey. Data is expressed as mean ± standard error of the mean (SEM) with data expressed as a percentage of CON-Veh
  2. aSignificantly different from CON-Veh
  3. bSignificantly different from AIE-Veh, p < 0.05