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Table 10 Study 2: Differential impact of AIE and galantamine on trophic and proinflammatory factors

From: Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure

Immunoblot marker

CON-Veh

CON-Gal

AIE-Veh

AIE-Gal

Pro-BDNF

100% ± 12

97% ± 12

111% ± 14

123% ± 13

Mature BDNF

100% ± 12

116% ± 12

94% ± 14

87% ± 13

Pan-Trk

100% ± 16

75% ± 15

87% ± 20

136% ± 9b

IRβ

100% ± 11

98% ± 11

90% ± 13

103% ± 12

IGF2 Precursor

100% ± 10

127% ± 30

93% ± 15

101% ± 15

Mature IGF2

100% ± 20

86% ± 20

104% ± 23

79% ± 21

Gp91phox

100% ± 17

77% ± 16

131% ± 19a

120% ± 17a

  1. Immunoblot quantification using Li-Cor Odyssey. Data is expressed as mean ± standard error of the mean (SEM) with data expressed as a percentage of CON-Veh
  2. aSignificantly different from CON-Veh
  3. bSignificantly different from AIE-Veh, p < 0.05