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Table 7 Study 1: Galantamine prevention of hippocampal neuroimmune induction after AIE

From: Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure

Neuroimmune CON-Veh CON-Gal AIE-Veh AIE-Gal
CCL2 216 ± 14 (100%) 226 ± 12 (105%) 316 ± 14 (148%)a 212 ± 12 (99%)b
HMGB1 780 ± 97 (100%) 820 ± 88 (103%) 1092 ± 102 (137%)a 761 ± 88 (95%)b
COX-2 289 ± 17 (100%) 280 ± 16 (98%) 349 ± 18 (119%)a 315 ± 15 (109%)
  1. Immunohistochemical stains (cells/mm2). Data is expressed as mean ± standard error of the mean (SEM); % change relative to CON-Veh rats are represented in parentheses to the right of each datapoint
  2. aSignificantly different from CON-Veh
  3. bSignificantly different from AIE-Veh