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Table 7 Study 1: Galantamine prevention of hippocampal neuroimmune induction after AIE

From: Galantamine prevents and reverses neuroimmune induction and loss of adult hippocampal neurogenesis following adolescent alcohol exposure

Neuroimmune

CON-Veh

CON-Gal

AIE-Veh

AIE-Gal

CCL2

216 ± 14 (100%)

226 ± 12 (105%)

316 ± 14 (148%)a

212 ± 12 (99%)b

HMGB1

780 ± 97 (100%)

820 ± 88 (103%)

1092 ± 102 (137%)a

761 ± 88 (95%)b

COX-2

289 ± 17 (100%)

280 ± 16 (98%)

349 ± 18 (119%)a

315 ± 15 (109%)

  1. Immunohistochemical stains (cells/mm2). Data is expressed as mean ± standard error of the mean (SEM); % change relative to CON-Veh rats are represented in parentheses to the right of each datapoint
  2. aSignificantly different from CON-Veh
  3. bSignificantly different from AIE-Veh