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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway

Fig. 2

NAD+ treatment mitigated CCH-induced learning and memory impairment. A The escape latency of rats in the training trials of hidden platform task. B The number of crossing the platform in the probe trial. C Relative time spent in the target quadrant in the probe trial. D Swimming speed in the probe trial. Values are expressed as mean ± SEM (n = 10). E The representative search traces of  rats in hidden platform test. F The representative search traces of rats in probe text. *P < 0.05; **P < 0.01 CCH vs. sham; #P < 0.05; NAD+ vs. CCH

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