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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway

Fig. 4

NAD+ alleviated ROS generation and mitochondrial injury. A Representative DHE fluorescence staining for ROS in the hippocampus and cortex (scale bars = 50 μm). B Relative level of ROS (ratio to sham group). Data are expressed as mean ± SEM (n = 3). *P < 0.05; **P < 0.01 vs. CCH. C Representative TEM micrographs of mitochondria in hippocampal microglia (scale bars = 5 μm or 1 μm)

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