Fig. 4From: NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathwayNAD+ alleviated ROS generation and mitochondrial injury. A Representative DHE fluorescence staining for ROS in the hippocampus and cortex (scale bars = 50 μm). B Relative level of ROS (ratio to sham group). Data are expressed as mean ± SEM (n = 3). *P < 0.05; **P < 0.01 vs. CCH. C Representative TEM micrographs of mitochondria in hippocampal microglia (scale bars = 5 μm or 1 μm)Back to article page