Skip to main content

Table 1 Statistics and n’s for experiments shown in Figs. 1, 2, 3, 4, and 5

From: Aging triggers an upregulation of a multitude of cytokines in the male and especially the female rodent hippocampus but more discrete changes in other brain regions

 

YM

YF

MM

MF

OM

OF

    

Figure

  

n=

  

Normality

EVa

effect of age

Effect of sexb

1A

4

3

  

4

3

Pass

Fail

Rank sum: T(7,7)=35.00, FDR-P=0.036

 

1B

4

3

  

4

3

Pass

Fail

Rank sum: T(7,7)=30.50, FDR-P=0.013

 

1C

4

3

  

4

3

Pass

Pass

Student’s t: t(12)=-3.472, FDR-P=0.019

 

1D

4

3

  

4

3

Pass

Pass

Student’s t: t(12)=-2.375, FDR-P=0.044

 

1E

4

3

  

4

3

Pass

Pass

Student’s t: t(12)=-3.128, FDR-P=0.023

 

1F

2

1

  

2

1

Pass

Pass

Student’s t: t(4)=-1.53, FDR-P=0.178

 

1G

4

3

  

4

3

Pass

Fail

Rank sum: T(7,7)=31.00, FDR-P=0.019

 

1H

4

3

  

4

3

Pass

Pass

Student’s t: t(12)=-2.340, FDR-P=0.044

 

1I

4

3

  

4

3

Fail

 

Rank sum: T(7,7)=32.00, FDR-P= 0.023

 

1J

4

3

  

4

3

Fail

 

Rank sum: T(7,7)=32.00, FDR-P=0.023

 

1K

4

3

  

4

3

Pass

Pass

Student’s t: t(12)=-5.641, FDR-P=0.002

 

1L

4

3

  

4

3

Fail

 

Rank sum: T(7,7)=28.50, FDR-P=0.007

 

1M

4

3

  

4

3

Pass

Fail

Rank sum: T(7,7)=34.00, FDR-P=0.029

 

1N

4

3

  

4

3

Fail

 

Rank sum: T(7,7)=28.00, FDR-P=0.007

 

1O

4

3

  

4

3

Fail

 

Rank sum: T(7,7)=33.50, FDR-P=0.025

 

1P

4

3

  

4

3

Pass

Pass

Student’s t: t(12)=−1.052, FDR-P=0.314

 

1Q

4

3

  

4

3

Pass

Pass

Student’s-t: t(12)=-2.386, FDR-P=0.044

 

1R

4

3

  

4

3

Pass

Pass

Student’s t: t(12)=-2.996, FDR-P=0.025

 

1S

4

3

  

4

3

Fail

 

Rank sum: T(7,7)=41.00, FDR-P=0.179

 

1T

4

3

  

4

3

Pass

Pass

Student’s t: t(12)=-2.554, FDR-P=0.036

 

1U

4

3

  

4

3

Fail

 

Rank sum: T(7,7)=33.00, FDR-P=0.025

 

1V

4

3

  

4

3

Pass

Pass

Student’s t: t(12)=-2.836, FDR-P=0.027

 

1W

4

3

  

4

3

Pass

Fail

Rank sum: T(7,7)=34.50, FDR-P=0.026

 

2A-left

7

7

4

4

8

6

Fail

 

ANOVA on ranks: H(2)=1.51, P=0.471

Rank sum: T(6,8)=47.0, P=0.852

2A-right

7

7

4

4

8

6

Pass

Fail

ANOVA on ranks: H(2)=8.505, P=0.014c

Rank sum: T(5,8)=41.0, P=0.435

2B

13

13

17

16

16

13

Fail

 

ANOVA on ranks: H(2)=44.227, P<0.001c

Rank sum: T(13,16)=252.00, P=0.013

2C-left

9

5

  

9

4

Pass

Fail

Rank sum: T(13,14)=226.00, P=0.035

Rank sum: T(4,9)=31.0, P=0.70

2C-right

9

5

  

9

4

Pass

Fail

Rank sum: T(13,14)=247.00, P=0.002

Rank sum: T(4,9)=30.0, P=0.817

3A

9

8

12

11

17

14

Fail

 

ANOVA on Ranks: H(2) = 50.059, P<0.001c

Rank sum: T(14,17)=230.0, P=0.827

3B-left

6

5

  

5

5

Pass

Pass

2-Way ANOVA: F(1,17)=11.207, P=0.004

2-Way ANOVA: F(1,17)=0.01, P=0.928

3B-right

6

5

  

5

5

Pass

Pass

2-Way ANOVA: F(1,17)=11.443, P=0.004

2-Way ANOVA: F(1,17)=0.003, P=0.955

3C

15

12

  

9

14

Fail

 

Rank sum: T(23,27)=289.0, P<0.001

Rank sum: T(4,8)=23.0, P=0.683

3D-left

2

3

  

2

3

Pass

Pass

Student’s t: t(8)=0.43, P=0.677

 

3D-right

2

3

  

2

3

Pass

Pass

Student’s t: t(8)=0.18, P=0.862

 

3E

16

13

  

10

10

Pass

Pass

2-Way ANOVA: F(1,45)=74.93, P<0.001

2-Way ANOVA: F(1,16)=0.22, P=0.649

3F-left

11

6

 

11

7

Fail

  

Rank sum: T(17,18)=270.5, P=0.248

Rank sum: T(7,11)=50.0, P=0.147

3F-right

11

7

 

11

7

Pass

Fail

 

Rank sum: T(18,18)=328.0, P=0.887

Rank sum: T(7,11)=46.0, P=0.07

3G

14

13

16

17

16

16

Fail

 

ANOVA on ranks: H(2)=53.334, P<0.001c

Rank sum: T(15,16)=207.0, P=0.199

3H

9

9

4

4

9

9

Pass

Pass

2-Way ANOVA: F(2,38)=1.90, P=0.163

2-Way ANOVA: F(1,6)=0.37, P=0.564

4A

2

5

  

2

5

Pass

Fail

Rank sum: T(7,7)=30.0, P=0.002

 

4B

2

5

  

2

5

Fail

 

Rank sum: T(7,7)=28.0, P<0.001

 

4C

2

5

  

2

5

Fail

 

Rank sum: T(7,7)=29.0, P=0.001

 

4D

2

5

  

2

5

Fail

 

Rank sum: T(7,7)=28.0, P<0.001

 

4E

2

5

  

2

5

Pass

Pass

Student’s t: t-test: t(12)=-4.01, P=0.002

 

4F

5

5

  

5

5

Pass

Pass

2-Way ANOVA: F(1,16)=55.42, P<0.001

2-Way ANOVA: F(1,16)=0.002, P=0.966

4G

5

5

  

5

5

Pass

Pass

2-Way ANOVA: F(1,16)=55.42, P<0.001

2-Way ANOVA: F(1,16)=14.36, P=0.002

5A-nuc

7

2

  

6

2

Pass

Fail

Rank sum: T(8,9)=108.0, P<0.001

 

5A-cyto

7

2

  

6

2

Fail

 

Rank sum: T(8,9)=108.0, P<0.001

 

5A-memb

7

2

  

6

2

Fail

 

Rank sum: T(8,9)=105.0, P=0.002

 

5B-nuc

7

2

  

6

2

Pass

fail

Rank sum: T(8,9)=107.0, P<0.001

 

5B-cyto

7

2

  

6

2

Fail

 

Rank sum: T(8,9)=105.0, P=0.002

 

5B-memb

6

2

  

6

2

Fail

 

Rank sum: T(8,8)=36.0, P<0.001

 
  1. YM young males, YF young females, MM middle-aged males, MF middle-aged females, OM old males, OF old females, EV equal variance, FDR corrected for multiple comparisons using false detection rate
  2. aEqual variance only tested when dataset passed normality
  3. bEffect of sex only analyzed in experiments where n>4/sex/age. Rank sum used when 2-way ANOVA for age x sex failed normality or equal variance and reports effect of sex within old mice. 2-way ANOVA used when normality and equal variance pass and reports main effect of sex across ages
  4. cSee the “Results” section for post hoc tests
Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094