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Table 2 Comparison between the controls and the patients with stroke (at baseline before thrombectomy)

From: Plasma neurofilament light chain level predicts outcomes in stroke patients receiving endovascular thrombectomy

 

Control (n = 14)

Stroke (n = 60)

P value

Age

66.0±1.41

71.2±11.8

0.001

Male sex

8 (57.1%)

34 (56.7%)

0.97

Hypertension

12 (85.7)

39 (65.0%)

0.20

Diabetes mellitus

5 (35.7%)

22 (36.7%)

0.95

Hyperlipidemia

10 (71.4%)

33 (55.0%)

0.37

Atrial fibrillation

5 (35.7%)

37 (61.7%)

0.13

NfL pg/ml

9.44 (7.73, 13.0)

33.3 (19.6, 88.9)

0.046

GFAP pg/mL

82.9 (55.3, 114.0)

238.8 (146.0, 330.5)

0.015

Tau pg/mL

1.62 (1.12, 2.00)

1.71 (0.97, 2.87)

0.26

UCHL1 pg/mL

7.30 (4.13, 13.5)

83.6 (64.8, 107.6)

<0.001

Log NfL

2.33±0.37

3.74±1.17

<0.001

Log GFAP

4.35±0.50

5.63±0.97

<0.001

Log Tau

0.31±0.75

0.38±1.12

0.61

Log UCHL1

1.95±0.91

4.41±0.40

<0.001

  1. The count and continuous variables are expressed as numbers (percentages) and as mean ± standard deviations, respectively, except for the raw biomarker data, which are presented as medians (first quartile, third quartile) because of their nonnormal distributions. The Mann–Whitney U test was used for the raw biomarker data, a t test was used for the natural log–transformed biomarkers, and the P values for biomarkers were adjusted for age