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Table 3 Changes in biomarker levels according to different outcomes

From: Plasma neurofilament light chain level predicts outcomes in stroke patients receiving endovascular thrombectomy

 

Time points

Overall (n = 60)

TICI 2c–3 (n = 43)

TICI 0–2b (n = 17)

mRS 0–2 (n = 32)

mRS 3–6 (n = 28)

No ICH (n = 40)

HI (n = 14)

PH (n = 6)

NfL

T1

3.74±1.17

3.80±1.19

3.58±1.13

3.55±1.27

3.95±1.03

3.86±1.19

3.42±0.71

3.66±1.84

T2

3.70±1.23

3.76±1.26

3.55±1.16

3.48±1.33

3.95±1.62

3.83±1.25

3.36±0.76

3.65±1.91

T3

4.30±1.15

4.35±1.13

4.14±1.22

3.95±1.09

4.79±1.06

4.35±1.22

3.91±0.55

4.69±1.37

  

P<0.001

PTICI=0.42, Pinteraction=0.63

PmRS=0.09, Pinteraction=0.06

PICH=0.43, Pinteraction=0.88

GFAP

T1

5.63±0.97

5.56±0.85

5.82±1.25

5.50±0.99

5.78±0.96

5.64±0.96

5.64±1.00

5.55±1.16

T2

5.76±0.99

5.66±0.87

6.02±1.23

5.60±0.98

5.95±0.98

5.73±0.98

5.77±1.02

5.94±1.16

T3

7.81±1.79

7.83±1.77

7.76±1.95

7.50±1.64

8.25±1.94

7.44±1.60

8.08±1.98

9.99±1.32

  

P<0.001

PTICI=0.41, Pinteraction=0.23

PmRS=0.09, Pinteraction=0.44

PICH=0.14, Pinteraction=0.005

Tau

T1

0.38±1.12

0.44±1.15

0.23±1.06

0.39±1.28

0.37±0.93

0.55±1.10

0.21±0.98

−0.37±1.39

T2

0.76±0.90

0.83±0.83

0.58±1.07

0.83±0.89

0.68±0.92

0.89±0.90

0.48±0.73

0.51±1.20

T3

1.43±1.35

1.36±1.48

1.69±0.67

1.30±1.18

1.61±1.57

1.51±1.48

1.04±1.03

1.60±0.70

  

P<0.001

PTICI=0.86, Pinteraction=0.43

PmRS=0.83, Pinteraction=0.35

PICH=0.31, Pinteraction=0.39

UCHL1

T1

4.41±0.40

4.41±0.42

4.40±0.37

4.39±0.39

4.42±0.42

4.41±0.41

4.49±0.40

4.18±0.35

T2

4.41±0.41

4.39±0.44

4.46±0.32

4.32±0.42

4.51±0.37

4.40±0.40

4.46±0.47

4.33±0.39

T3

4.83±0.69

4.81±0.67

4.89±0.79

4.65±0.54

5.08±0.81

4.71±0.62

4.87±0.69

5.61±0.81

  

P<0.001

PTICI=0.69, Pinteraction=0.67

PmRS=0.04, Pinteraction=0.04

PICH=0.52, Pinteraction=0.007

  1. PTICI, PmRS, PICH = overall group difference, Pinteraction= whether groups diverged differently over time. ICH intracerebral hemorrhage, HI hemorrhagic infarction, PH parenchymal hemorrhage