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Table 3 Changes in biomarker levels according to different outcomes

From: Plasma neurofilament light chain level predicts outcomes in stroke patients receiving endovascular thrombectomy

  Time points Overall (n = 60) TICI 2c–3 (n = 43) TICI 0–2b (n = 17) mRS 0–2 (n = 32) mRS 3–6 (n = 28) No ICH (n = 40) HI (n = 14) PH (n = 6)
NfL T1 3.74±1.17 3.80±1.19 3.58±1.13 3.55±1.27 3.95±1.03 3.86±1.19 3.42±0.71 3.66±1.84
T2 3.70±1.23 3.76±1.26 3.55±1.16 3.48±1.33 3.95±1.62 3.83±1.25 3.36±0.76 3.65±1.91
T3 4.30±1.15 4.35±1.13 4.14±1.22 3.95±1.09 4.79±1.06 4.35±1.22 3.91±0.55 4.69±1.37
   P<0.001 PTICI=0.42, Pinteraction=0.63 PmRS=0.09, Pinteraction=0.06 PICH=0.43, Pinteraction=0.88
GFAP T1 5.63±0.97 5.56±0.85 5.82±1.25 5.50±0.99 5.78±0.96 5.64±0.96 5.64±1.00 5.55±1.16
T2 5.76±0.99 5.66±0.87 6.02±1.23 5.60±0.98 5.95±0.98 5.73±0.98 5.77±1.02 5.94±1.16
T3 7.81±1.79 7.83±1.77 7.76±1.95 7.50±1.64 8.25±1.94 7.44±1.60 8.08±1.98 9.99±1.32
   P<0.001 PTICI=0.41, Pinteraction=0.23 PmRS=0.09, Pinteraction=0.44 PICH=0.14, Pinteraction=0.005
Tau T1 0.38±1.12 0.44±1.15 0.23±1.06 0.39±1.28 0.37±0.93 0.55±1.10 0.21±0.98 −0.37±1.39
T2 0.76±0.90 0.83±0.83 0.58±1.07 0.83±0.89 0.68±0.92 0.89±0.90 0.48±0.73 0.51±1.20
T3 1.43±1.35 1.36±1.48 1.69±0.67 1.30±1.18 1.61±1.57 1.51±1.48 1.04±1.03 1.60±0.70
   P<0.001 PTICI=0.86, Pinteraction=0.43 PmRS=0.83, Pinteraction=0.35 PICH=0.31, Pinteraction=0.39
UCHL1 T1 4.41±0.40 4.41±0.42 4.40±0.37 4.39±0.39 4.42±0.42 4.41±0.41 4.49±0.40 4.18±0.35
T2 4.41±0.41 4.39±0.44 4.46±0.32 4.32±0.42 4.51±0.37 4.40±0.40 4.46±0.47 4.33±0.39
T3 4.83±0.69 4.81±0.67 4.89±0.79 4.65±0.54 5.08±0.81 4.71±0.62 4.87±0.69 5.61±0.81
   P<0.001 PTICI=0.69, Pinteraction=0.67 PmRS=0.04, Pinteraction=0.04 PICH=0.52, Pinteraction=0.007
  1. PTICI, PmRS, PICH = overall group difference, Pinteraction= whether groups diverged differently over time. ICH intracerebral hemorrhage, HI hemorrhagic infarction, PH parenchymal hemorrhage