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Fig. 4 | Journal of Neuroinflammation

Fig. 4

From: Dexamethasone enhances the efficacy of atorvastatin in inhibiting excessively inflammation-induced abnormal angiogenesis by regulating macrophages

Fig. 4

Effects of ATO and DEX on the expression of M2 markers. a Representative images of western blots showing CD206, SR-BI and Arg-1 expression. b Quantification of CD206, one-way ANOVA, P = 0.001; compared with the LPS group, Bonferroni test, ***P = 0.003, *P < 0.05. LPS+0.01D+0.1A group vs. LPS+0.01D group, unpaired Student’s t test, P = 0.009. c Quantification of SR-BI, one-way ANOVA, P < 0.001; compared with the LPS group, Bonferroni test, ***P < 0.005, *P = 0.044. LPS+0.01D+0.1A group vs. LPS+0.1A group, unpaired Student’s t test, P = 0.021. d Quantification of Arg-1, one-way ANOVA, P = 0.006; compared with the LPS group, Bonferroni test, **P = 0.007, *P < 0.05. e The mRNA expression of IL-10, one-way ANOVA, P < 0.001; compared with the LPS group, the Bonferroni test, ***P = 0.001, *P = 0.031. LPS+0.01D+0.1A group vs. LPS+0.1A group, unpaired Student’s t test, P = 0.012, LPS+0.01D+0.1A group vs. LPS+0.01D group, unpaired Student’s t test, P = 0.026. Note: A, atorvastatin; Arg-1, Arginase-1; D, dexamethasone; SR-B1, Scavenger receptor class B type I

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