Fig. 3
Co-expression analysis of the kynurenine pathway in the post-mortem prefrontal cortex. A The network model of the kynurenine pathway in the post-mortem prefrontal cortex. Samples with the highest and lowest expression levels were selected for the analysis. The white arrows show signal transduction between upstream and downstream elements. Black arrows indicate significant co-expression with the downstream element. Filled circles indicate a significant correlated or changed element in interaction analysis (p < 0.05). B Correlations using Pearson1 or Spearman2 analysis of the samples with the highest expression and lowest expression of upstream elements among all 29 samples were selected. Significant interactions are indicated with bold (p < 0.05)