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Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: Small extracellular vesicles encapsulating CCL2 from activated astrocytes induce microglial activation and neuronal apoptosis after traumatic spinal cord injury

Fig. 3

sEVs released by activated astrocytes induce microglial activation and neuronal apoptosis. ac ELISA method to detect the expression of TNF-α, IL-1β, and IL-6. d Detection of changes in NO content. e, f Transwell assessment of the migration ability of BV2 microglia. g, h TUNEL staining detecting neuronal apoptosis. i, j Western blotting detecting the expression of apoptosis-related proteins in neurons

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