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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: HMGB1 mediates cognitive impairment caused by the NLRP3 inflammasome in the late stage of traumatic brain injury

Fig. 5

Glycyrrhizin inhibits the activation of NLRP3 inflammasome. AC Western blot band and analysis indicating that the level of NLRP3 and caspase-1 (p20) were significantly reduced in TBI groups. Data represent the means ± SD (n = 3 per group), Unpaired t-test. *p < 0.05, **p < 0.01 compared to the sham group (D). Immunofluorescence revealed that NLRP3 and Caspase-1 level were significantly reduced by glycyrrhizin treatment

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