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Table 1 Table demonstrating cytokine and chemokine levels of whole brain lysate

From: Neurofilament light: a possible prognostic biomarker for treatment of vascular contributions to cognitive impairment and dementia

  Cytokine and chemokine, relative expression (pg/ml) p values
Cytokines Control-Saline (n=5-6) HF-Saline (n=6) HF-A50 (n=6-7) HF-P50 (n=6-7) HF-A500 (n=7) HF-P500 (n=7) Control-Saline vs. HF-Saline HF-Saline vs. HF-P50 HF-Saline vs. HF-A50 HF-Saline vs. HF-P500 HF-Saline vs. HF-A500
IL-1α 92.8 ±5.9 74.7 ±5.4 95.6 ±8.4 103.7 ± 8.1 95.6 ± 5.5 65.4 ±9.7 0.048* 0.027* ns ns 0.040*
IL-2 46.8 ±1.1 38.4 ±1.7 47.8 ±3.0 54.3 ± 3.5 50.9 ± 1.9 40.9 ±4.6 0.015* 0.013* ns ns 0.002*
IL-5 59.5 ±14.0 28.0 ±9.2 62.6 ±3.9 62.6 ±3.9 53.2 ±2.7 41.7 ±4.9 ns 0.020* 0.026* ns ns
IL-13 481.1 ±33.4 385.9 ±14.8 529.9 ±38.6 543.8 ±15.6 510.0 ±17.3 394.0 ±47.6 ns <0.0001* 0.036* ns 0.001*
IL-17 40.0 ±1.7 32.4 ±1.1 44.1 ± 2.8 43.0 ±1.9 42.0 ±1.1 35.2 ±4.6 0.021* 0.004* 0.020* ns 0.0003*
IL-10 45.5 ±4.4 32.1 ±1.1 42.2 ±3.2 40.8 ±2.5 43.8 ±4.2 40.4 ±1.5 0.049* 0.023* ns 0.005* ns
  1. IL-1α, IL-2, IL-5, IL-13, IL-17, and IP-10, mean, standard error and number of samples are provided for the following treatment groups: Control-Saline, HF-Saline, HF-A50 (Ang-(1–7), Ang-(1–7)50 ug/kg), HF-P50 (PNA5 50 ug/kg), HF-A500 (Ang-(1–7)500 ug/kg), and HF-P500 (PNA5 500ug/kg). Significant difference between treatment groups and HF-Saline are provided, *Indicates significance, p < 0.05, (ANOVA, Dunnett’s post hoc), ns not significant)