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Table 3 Longitudinal values of HF-induced inflammation comparing plasma cytokines at 3 weeks post-MI to 8 weeks post-MI

From: Neurofilament light: a possible prognostic biomarker for treatment of vascular contributions to cognitive impairment and dementia

  Cytokine and chemokine, relative expression p values
  3 weeks HF 3 weeks HF 8 weeks HF 8 weeks HF 3 weeks Control-Saline vs. 3 weeks HF-Saline 3 weeks Control-Saline vs. 3 weeks HF-Saline 3 weeks HF-Saline vs. 8 weeks HF-Saline
Cytokines Control-Saline (n=5) HF-Saline (n=7) Control-Saline (n=6) HF-Saline (n=6)
IL-1α 176.1 ± 34.8 882.3 ±198.4 92.8 ± 5.9 74.7 ±5.4 0.003* 0.964 0.0004*
MIP-1α 32.6 ±9.7 67.9 ±6.6 6.8 ± 1.2 6.4 ±1.3 0.002* 0.027* <0.0001*
MIP-2 65.0 ±11.4 155.9 ±17.0 45.2 ±6.3 54.1 ±14.7 0.0009* 0.764 0.0001*
  1. Mean, Standard error, and number of sample values of plasma IL-1α, MIP-1α, and MIP-2 from 3 and 8 weeks post-MI are represented for both treatment groups Control-Saline, and HF-Saline. P values of the following comparison are provided: 3 weeks post-MI Control-Saline and 3 weeks post-MI HF-Saline, 3 weeks post-MI Control-Saline and 8 weeks post-MI Control-Saline, and 3 weeks post-MI HF-Saline and 8 weeks post-MI HF-Saline. *Indicates significance, p < 0.05, (ANOVA, Tukey’s post), ns not significant