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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Macrophage-specific RhoA knockout delays Wallerian degeneration after peripheral nerve injury in mice

Fig. 1

Identification of macrophage-specific knockout of RhoA. a F4/80 and RhoA double-immunofluorescent staining in the crush injured sciatic nerve at 7 dpi, which showing that even RhoA is expressed in the injured nerve but is negative in the F4/80+ macrophages in the cKO Group. Scale bars: 50 µm. b, c Western blots and statistical analysis showing the level of RhoA protein in the injured nerve is significantly decreased in the cKO group comparing to the Cre group. df Immunocytochemistry and Western blots showing that RhoA expression is hard to be detected in the isolated macrophages in vitro. Scale bars: 50 µm. The data are presented as the mean ± SEM values (n = 6 per group)

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