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Fig. 2 | Journal of Neuroinflammation

Fig. 2

From: Regulation of the p75 neurotrophin receptor attenuates neuroinflammation and stimulates hippocampal neurogenesis in experimental Streptococcus pneumoniae meningitis

Fig. 2

The expression of proBDNF/p75NTR and p75NTR cellular distribution at 24 h after PM induction. a, b Western blot analysis of proBDNF/p75NTR protein levels in the cortex and hippocampus at 24 h post-infection. Proteins were normalized to β-actin. c Representative immunofluorescence colocalization images of p75NTR/NeuN, p75NTR/Iba1, p75NTR/GFAP in the cortex at 24 h post-infection. Neuron cells, microglial cells, and astrocytes are labeled with NeuN (green), Iba-1 (green), and GFAP (green), respectively. (p75NTR = red and DAPI = blue). Data are presented as the mean ± SEM (n = 2–6 rats). **p < 0.01. Scale bar = 20 μm

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