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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Blockade of the NLRP3/caspase-1 axis attenuates ketamine-induced hippocampus pyroptosis and cognitive impairment in neonatal rats

Fig. 1

MCC950 or VX765 attenuates the loss of nerve cells in the hippocampus of neonatal rat exposure to ketamine. A Nissl staining hippocampus (CA1, CA3, and DG region). Hippocampus was viewed at a magnification of 40×; the others, at 400×. B Number of cells in CA1, CA3, DG area. Values are expressed as mean ± SD. *P < 0.05, **P < 0.01, compared with group C; # P < 0.05, ##P < 0.01, compared with group Ket. Con, control; Ket, ketamine. CA1, Cornu Ammonis 1, CA3, Cornu Ammonis 3. DG, Gentate Gyrus

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