Fig. 10From: Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer’s diseaseSchematic showing plausible mechanism behind the study outcome. Top panel shows how LPS may induce EP2 mediated neuroinflammation in two-hit AD brains, where both single-hits (environmental and genetic) act in synergy. Bottom panel shows how EP2 receptor antagonist (TG11-77.HCl) ameliorates neuroinflammation selectively in the two-hit AD brainsBack to article page