Fig. 2
Effects of diabetes on the antibody production and B cells differentiation in EAMG rats. Serum anti-R97–116 IgG (A), IgG1 (B), IgG2a (C), and IgG2b (D) were determined by ELISA. Percentages of IgGhi ASCs (E), Igκhi ASCs (F), and memory B cells (G) were assessed by flow cytometry and representative dot plot were shown, respectively. Data were from two independent experiments and expressed as mean ± SEM. n = 8 in the DM+EAMG group and n = 7 in the EAMG group. The significance of differences was assessed by the Unpaired Student’s t test. ns means not significant, *p < 0.05 and ***p < 0.01