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Table 2 Association between baseline anti-GM1 and anti-GD1a antibodies and prognostic

From: Autoantibody screening in Guillain–Barré syndrome

Univariate and Multivariable logistic analysis for inability to walk independently at 6 months

Variable

OR

95% CI

p

Univariate analysis

GM1 IgG

3.2

1.05–9.71

0.04

GD1a IgG

0.48

0.05–4.24

0.515

logNFL

3.22

1.46–7.14

0.004

AMAN

2.97

0.73–12.07

0.127

Diarrhoea

3.64

1.21–10.91

0.021

Age

1.05

1.01–1.10

0.005

Initial GDS

3.15

1.38–7.18

0.006

Multivariable logistic analysis

logNfL

3.13

1.27–7.67

0.012

Age

1.05

1.01–1.10

0.013

Univariate and Multivariable logistic analysis for inability to walk independently at 1 year

Variable

OR

95% CI

p

Univariate analysis

GM1 IgG

5.09

1.38–18.73

0.014

GD1a IgG

0.92

0.10–8.44

0.944

logNFL

3.11

1.27–7.55

0.012

AMAN

1.475

0.27–7.97

0.652

Diarrhoea

2.7

0.74–9.82

0.131

Age

1.06

1.01–1.11

0.014

Initial GDS

2.79

1.12–6.93

0.027

Multivariable logistic analysis

GM1 IgG

6.98

1.60–30.36

0.01

Age

1.07

1.01–1.12

0.01

Univariate and Multivariable logistic analysis for inability to run independently at 1 year

Variable

OR

95% CI

p

Univariate analysis

GM1 IgG

4.16

1.39–12.49

0.011

GD1a IgG

0.72

0.13–3.99

0.710

logNFL

4.37

1.95–9.78

 < 0.0001

AMAN

6.53

1.57–27.17

0.01

Diarrhoea

2.33

0.83–6.57

0.109

Age

1.04

1.01–1.07

0.023

Initial GDS

1.81

1.08–3.04

0.025

Multivariable logistic analysis

Age

1.04

1.01–1.08

0.022

AMAN

6.19

1.01–38.02

0.049

logNfL

3.17

1.34–7.50

0.009

  1. logNfL log-transformed neurofilament light chain; AMAN acute motor axonal neuropathy; GDS Guillain–Barré Syndrome Disability Score
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Journal of Neuroinflammation

ISSN: 1742-2094