Fig. 7
From: Interleukin-6 mediates delirium-like phenotypes in a murine model of urinary tract infection
Systemic IL-6 inhibition significantly improves UTI-induced impairments in the Y-maze test. a, b In the Y-maze test, total spontaneous alternations in 5 min (ANOVA, F = 6.310, dF = 30, p = 0.0085) and the first ten alternations (ANOVA, F = 17.18, dF = 30, p < 0.0001) were markedly reduced in the UTI group in comparison to the control or UTI + α-IL-6 groups. Each dot represents one animal (n = 9 in control, n = 10 in UTI, n = 12 in UTI + α-IL-6). Behavioral tests were performed 48 h after inoculation. Quantitative data are expressed in mean ± SD. *p < 0.05, **p < 0.01, ****p < 0.0001