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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Altered expression of fragile X mental retardation-1 (FMR1) in the thymus in autoimmune myasthenia gravis

Fig. 1

Analyses of CGG triplets in FMR1 5’UTR in the thymus of MG patients. Analysis of CGG repeat length using the AmplideX® FMR1 PCR kit. DNA was extracted from thymic biopsies. A Comparison of MG patients (n = 80) and non-MG patients (n = 48). Here to compare the number of CGG triplets in males and females, the mean of CGGs on both alleles of the X chromosome was calculated for females. B Distribution of the number of CGG triplets in MG patients and non-MG patients. C Comparison of female and male MG patients (n = 58 females and 22 males) and non-MG patients (n = 38 females and 10 males). D, E Separate analyses of the shorter D or longer E CGG sequences on each chromosome X in females. F Comparison of the number of CGG triplets on DNA extracted from thymic and blood cells from a same MG patients. p values were assessed with an unpaired t-test (A), a Mann–Whitney test (CE), and a Wilcoxon test (F)

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