Fig. 2
From: Appearance of claudin-5+ leukocyte subtypes in the blood and CNS during progression of EAE
Appearance of CLN-5+ CD45+ cells in blood/CNS during EAE. At the indicated days (D) following EAE induction, peripheral blood and CNS (brain + spinal cord) leukocytes were separately collected from individual mice, and analyzed by flow cytometry to identify CLN-5+ CD45+ cells. Number of CLN-5+ leukocytes and their percentage of the CD45+ population in blood/CNS are reported. Individual data points are overlaid for each group. Naïve mice received no injections, and control mice on D6 and D12 received adjuvants alone. Each experimental group contained six mice. Data are expressed as mean + SEM. Bars indicate comparison between groups. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001