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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Systemic inflammasome activation and pyroptosis associate with the progression of amnestic mild cognitive impairment and Alzheimer’s disease

Fig. 1

RNA-seq analysis of PBMCs isolated from patients with AD and controls. a GO-BP analysis showing the most significantly enriched signaling pathways in PBMCs. b GSEA of the genes associated with the “inflammatory response” in PBMCs based on the Gene Ontology Biological Process Database. Nominal P < 0.05. c Heatmap of genes with an adjusted P value < 0.05, false discovery rate < 0.05, and log2 fold-change > 1.5 from RNA-seq analysis of PBMCs. n = 8 for control, n = 10 for AD

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Journal of Neuroinflammation

ISSN: 1742-2094