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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: Tonicity-responsive enhancer-binding protein promotes diabetic neuroinflammation and cognitive impairment via upregulation of lipocalin-2

Fig. 6

Expression of LCN2 and TonEBP in LPS-treated RAW 264.7 macrophages is enhanced by HG treatment. a Western blot analysis of LCN2, TonEBP, and NF-κBp65 at 2, 6, 24 h after LPS treatment. b Western blot analysis of LCN2, TonEBP, NF-κBp6, and supernatant medium LCN2 in LPS-treated RAW 264.7 macrophages following HG treatment. c Western blot analysis of LCN2, TonEBP, and NF-κBp65 in cytosolic and nuclear fractions of LPS or LPS/HG-treated RAW 264.7 macrophages. p84 and PRXII are nuclear and cytosolic markers, respectively. d Representative immunofluorescence staining for LCN2 and TonEBP in CTL, HG, LPS, and LPS/HG-treated RAW 264.7 macrophages

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Journal of Neuroinflammation

ISSN: 1742-2094