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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Mechanisms underlying antidepressant effect of transcutaneous auricular vagus nerve stimulation on CUMS model rats based on hippocampal α7nAchR/NF-κB signal pathway

Fig. 10

Immunofluorescence staining of hippocampal sections in each group rats (α7nAchR) (n = 3, per group). Compared with α7nAchR(−/−) + taVNS group and Hi MLA + taVNS group, representative confocal images of brain sections shows more expression of α7nAchR (green) in Hi saline + taVNS group. The microglia transform from ameboid form (α7nAchR(−/−) + taVNS group and Hi MLA + taVNS group) to ramified state (Hi saline + taVNS). Compared with α7nAchR(−/−) + taVNS group and Hi MLA + taVNS group, the co-expression between α7nAchR (green) and microglia (red) increased in Hi saline + taVNS group. α7nAchR (green), Iba-1 (red), DAPI (blue), Merge (yellow); 40 times objective lens, scale bar: 100 μm and 20 μm magnification

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Journal of Neuroinflammation

ISSN: 1742-2094