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Fig. 7 | Journal of Neuroinflammation

Fig. 7

From: Mechanisms underlying antidepressant effect of transcutaneous auricular vagus nerve stimulation on CUMS model rats based on hippocampal α7nAchR/NF-κB signal pathway

Fig. 7

Immunofluorescence staining of hippocampal sections in each group rats (IL-1β) (n = 3, per group). Compared with control group and taVNS group, representative confocal images of brain sections shows more expression of IL-1β (green) in model group. The microglia transform from ramified morphology (control group) to ameboid form (model group) to ramified state (taVNS group). Compared with control group and taVNS group, the co-expression between pro-inflammatory cytokine IL-1β (green) and microglia (red) increased in model group, while the result was reversed in taVNS group. IL-1β (green), Iba-1 (red), DAPI (blue), Merge (yellow); 40 times objective lens, scale bar: 100 μm and 20 μm magnification

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Journal of Neuroinflammation

ISSN: 1742-2094