Skip to main content
Fig. 3 | Journal of Neuroinflammation

Fig. 3

From: MicroRNA-155-5p promotes neuroinflammation and central sensitization via inhibiting SIRT1 in a nitroglycerin-induced chronic migraine mouse model

Fig. 3

The administration of NTG increased miR-155-5p level and decreased the expression of SIRT1. A The expression level of miR-155-5p. B The mRNA expression of SIRT1. C The protein level of SIRT1. D The immunofluorescence intensity of SIRT1. E, F SIRT1 was partly coexpressed with Iba1, NeuN and GFAP in the TNC. After SRT1720 (a SIRT1 activator) treatment, the coexpression of SIRT1 and Iba1 increased, while the co-localization of SIRT1 and GFAP did not change. (n = 6–8 in each group; scale bar = 20 μm; **p < 0.01 and ****p < 0.0001 compared with the Sham group)

Back to article page

Journal of Neuroinflammation

ISSN: 1742-2094