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Fig. 6 | Journal of Neuroinflammation

Fig. 6

From: In vivo alterations of mitochondrial activity and amyloidosis in early-stage senescence-accelerated mice: a positron emission tomography study

Fig. 6

Immunostaining for TREM2 (green) and Iba1 (red) in the cerebral cortex of 15-week-old SAMR1 mice (A–C) and 5-week-old (D–F), 15-week-old (G–I) and 25-week-old (J–L) SAMP10 mice. M Quantification of the immunofluorescent signals. Note that TREM2 immuno-reactivity was higher and localized to the microglia in the 15- and 25-week-old SAMP10 mice. Arrowheads indicate TREM2 signals. Scale bar: 10 μm. Data are means ± SEs. They were analyzed by one-way ANOVA followed by the Bonferroni test (*p < 0.05). n = 4 for each group, except for 25-week-old SAMP10 mice (n = 2)

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