Fig. 3

VILI increases IL-1β in the lung and corpus callosum but not in the plasma at 2 week post injury. Multiplex ELISA shows increased IL-1β in the lung (A) and in the corpus callosum (C), but not in the plasma (B) of animals with VILI. N = 6 controls, 4 low Vt, and 5 high Vt. Data are presented as box plots showing the median, 25th to 75th percentile, and minimal to maximal value. Data was analyzed with the nonparametric Kruskal–Wallis test with Dunn’s post-test for multiple comparison, p values < 0.05 are shown on bars