Fig. 7From: Tracking macrophages in diabetic neuropathy with two-color nanoemulsions for near-infrared fluorescent imaging and microscopyQuantification of CD68 and DiI signal in hypodermal tissue surrounding the Neurovascular bundles of the hind limb foot pad. Analysis of the hypodermal regions (dotted white line) between metatarsals 2, 3 and 4 from hind limb foot pads of WT (n = 3) (A) and Leprdb/db (n = 3) (B) mice showed a significantly lower amount of DiI surrounding the nerves (N) of neurovascular bundles of Leprdb/db mice as compared to WT mice (p = 0.0063) (C). No significant difference was found for percent area of CD68 (p = 0.3389) (D) or Pearson’s correlation for CD68 and DiI (p = 0.7317) (E) when comparing WT and Leprdb/db mice. Scale bar = 200 µm. Error bar represents the standard deviation from twelve independent measurementsBack to article page