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Fig. 1 | Journal of Neuroinflammation

Fig. 1

From: Immunological status of the olfactory bulb in a murine model of Toll-like receptor 3-mediated upper respiratory tract inflammation

Fig. 1

A Protocol for generating the murine model of TLR3-mediated upper respiratory tract inflammation and images for analysis. Two groups of mice were received either poly(I:C), or vehicle to the right nostril. B Images and levels of cutting positions for the evaluation of OSNs and immune cells. The areas for evaluation of OSNs and immune cells are the nasal septum (i), the tegmen of the nasal cavity (ii), and the lateral wall of the nasal cavity (iii). Scale bar = 500 μm. C Images and levels of cutting positions for the evaluation of OB microglia/macrophages and astrocytes. The areas for the evaluation of the OB are GRL, EPL, and GML (Scale bar = 500 μm). EPL external plexiform layer, GML glomerular layer, GRL granular layer, OB olfactory bulb, OSNs olfactory sensory neurons, poly(I:C) polyinosinic–polycytidylic acid, TLR Toll-like receptor

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