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Fig. 5 | Journal of Neuroinflammation

Fig. 5

From: Immunological status of the olfactory bulb in a murine model of Toll-like receptor 3-mediated upper respiratory tract inflammation

Fig. 5

A Immunostained sections, showing TMEM119+ cells in the OB of the Control day 3 and Poly(I:C) day 3 groups (Scale bar = 100 μm). B Comparison of the TMEM119+ cell counts at day 3 in the GML, GRL, and EPL between the groups. C Comparison of the TMEM119+ cell counts at day 9 in the three described areas between the groups. D Comparison of the TMEM119+ cell counts at day 21 in the three described areas between the groups. E Immunostained sections, showing TMEM119+/Iba-1+ cells (arrow) and TMEM119/Iba-1+ cells (arrowhead) in the GRL, EPL, and GML of the Control day 3 and Poly(I:C) day 3 groups (Scale bar = 100 μm). Statistical analysis was performed using the Mann–Whitney U test, with P < 0.05 (*) and P < 0.01 (**) representing statistical significance. The error bars shown represent the standard error of the mean (n = 5). EPL external plexiform layer, GML glomerular layer, GRL granule layer, OB olfactory bulb, OSNs olfactory sensory neurons, Poly(I:C) polyinosinic–polycytidylic acid

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