Fig. 1

Lipidomic analysis of SPM synthesis pathways markers in the CNS of naïve and EAE mice. A, B Graphs showing the quantification of A DHA metabolome and B EPA metabolome in the spinal of naïve and EAE mice (n = 5 per group). Dotted line highlights the naïve value. *p < 0.05; **p < 0.01; vs. vehicle. Two-way ANOVA with repeated measures, Bonferroni’s post hoc test. Data are shown as mean ± SEM