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Fig. 10 | Journal of Neuroinflammation

Fig. 10

From: Administration of Maresin-1 ameliorates the physiopathology of experimental autoimmune encephalomyelitis

Fig. 10

Effects of MaR1 on neurological deficits and myelin loss in EAE mice. A, B Graphs showing the clinical score of EAE mice treated with MaR1 or vehicle over disease progression (A), as well as the maximum and cumulative EAE score (B). C Graph showing the quantification of myelin loss in the lumbar spinal cord of MaR1- or vehicle-treated mice at 21 days post-induction. D Representative histological spinal cord tissue sections stained with LFB from EAE mice treated with vehicle and MaR1. *p < 0.05; **p < 0.01; ***p < 0.001 vs. vehicle. Two-way ANOVA with repeated measures, Bonferroni’s post hoc test in A (n = 12 per group). Unpaired t-test in B (n = 12 per group) and C (n = 9 in vehicle and n = 11 in MaR1). Data were pooled from two different experiments. Data are shown as mean ± SEM

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